Marvel’s Deadpool VR Voice Actors: Full Cast Guide

Release Date: 18/11/2025
Developer: Twisted Pixel Games and published by Oculus Studios
Marvel's Deadpool VR is a hack and slash action game developed by Twisted Pixel Games and published by Oculus Studios. Released on November 18, 2025, this VR-exclusive title brings the Merc with a Mouth to life on Meta Quest 3 and Meta Quest 3S. With its signature humor, creative combat mechanics, and original story featuring fourth-wall breaks, Marvel's Deadpool VR offers one of the most entertaining superhero experiences available in virtual reality today.
Voice Acting: English

In Marvel’s Deadpool VR, you’ll step into the shoes of Wade Wilson after he gets pulled through a portal to Mojo World. The story kicks off when Deadpool signs a sketchy contract with Mojo to kidnap various Marvel villains for a reality show, leading to hilarious misadventures across the Marvel Universe. What makes this game special is how it captures Deadpool’s irreverent personality through its writing and character interactions.

Neil Patrick Harris voices Deadpool and brings a fresh take to the character that feels both unique and familiar. Harris, best known for his role as Barney Stinson on How I Met Your Mother and his work hosting major award shows, delivers the perfect comedic timing for Wade Wilson’s constant one-liners and fourth-wall breaks. His performance makes every combat encounter and story moment feel authentically Deadpool, even as you’re experiencing it in VR.

You’ll also encounter several iconic Marvel villains throughout your adventure. John Leguizamo, the versatile actor known for roles in Carlito’s Way and The Pest, voices Mojo, the reality-obsessed villain who recruits Deadpool for his interdimensional streaming network. Leguizamo’s distinctive voice adds personality and menace to Mojo’s character. The game also features Lady Deathstrike, Mephisto, Omega Red, and Ultimo as antagonists you’ll face off against, each bringing their own flavor to the combat encounters.

The voice acting across the board demonstrates that Twisted Pixel understood the assignment when it came to bringing these characters to life. The team worked closely with Marvel Games to ensure the performances captured the essence of these beloved characters while creating something that feels fresh for VR.

If you’re curious about the complete voice cast bringing these characters to life, dive into the full credits to discover who else lent their talents to make Marvel’s Deadpool VR such an entertaining experience.

THE Marvel’s Deadpool VR CAST

14 Voice Actors on MTVA
17 Characters on MTVA

THE MARVEL’S DEADPOOL VR CAST

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